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Robert Jervis
Affiliation: University of Toronto
Keywords: Nuclear analytical chemistry, aerosol physics & chemistry, characterizing air pollutants
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R. E. Jervis was among the pioneers in developing nuclear methods of analysis. He was especially instrumental in devising ways to apply nuclear reactions brought about in reactors and accelerators in studying trace substances down to the ppb level in chemical and biological systems. He was the first to study heavy metals including Hg, As, Pb, Cd, in the Canadian environment and diet using techniques of radioanalytical chemistry and has also pioneered, world-wide, the use of human tissues such as hair and nails to monitor bodily accumulation of toxic substances. Besides their use in the environment and in medicine, these techniques have opened several entirely new fields in forensic science.
Dr. Gyan Johari
Affiliation: McMaster University
Keywords: Amorphous solids, thermodynamics, dielectrics, physics of ice and glaciers, pharmaceutical's design and delivery
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Gyan P. Johari is Professor and Chair of Glass Science and Technology, Department of Materials Science and Engineering, McMaster University.
Professor Johari's research has contributed significantly to our understanding of amorphous substances: His considerations of the thermodynamics of structural relaxation and its effects on the properties of glasses have led him to formulate a well-received theory of hierarchically constrained molecular motions which begin at particular sites and evolve with time; he has contributed much to the theories of fast-ion conduction in ionic glasses, and of dynamically controlled chemical reactions, and developed the concept of negative feedback between molecular diffusion and chemical reaction in the gelation and vitrification of thermoset polymers. He has developed calorimetric methods for distinguishing between amorphous and microcrystalling states, and techniques for hyperquenching of micron-size droplets for the study of partially metabolized states of biopolymers.
Dr. Martin Johns
Affiliation: McMaster University
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Martin Wesley Johns, B.A., M.A. (McM.), Ph.D. (Tor.), is Professor of Physics at Hamilton College, McMaster University. He is known for his important contributions in the field of B- and y-ray spectroscopy. He and his students have built the first Siegbahn-type double-focusing B-ray spectrometers. With this instrument he has been able to establish the decay schemes for a number of radio-active nuclei. Dr. Johns has also been an active member of a medical research team interested in the detection and treatment of thyroid disorders.
Dr. Rose Johnstone
Affiliation: McGill University
Keywords: Reconstitution of transporters, selective modification of red cell plasma membranes, amino acid transport
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Dr. Johnstone did pioneering work in the isolation of plasma membranes from nucleated cells and her studies showed that isolated membranes had all the known properties for solute transport. A membrane potential difference was a major energy source for Na+ dependent transport. Her next important contribution was the introduction of fluorescent dyes to follow membrane potential changes during amino acid transport. From these studies it was determined that transport of neutral amino acids coupled to Na is electrogenic during influx as well as efflux. The direction of net flux of an amino acid could be a major determinant of the measured membrane potential. More recently Dr. Johnstone has been studying the loss of the transferrin receptor during reticulocyte maturation and demonstrated that this process involves the removal of plasma membrane proteins including the transferrin receptors and their release in a retrievable vesicle, the exosome.
Paul Jolicoeur
Affiliation: Université de Montréal
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Paul Jolicoeur (M.D., Ph.D.) is Director of the Molecular Biology Laboratory of CRIM and an eminent biomedical researcher in the field of retroviruses and cancer. Major contributions have been on the molecular control of the Fv-1 gene, on the identification of several determinants of pathogenecity of murine leukemia retroviruses and on the isolation of revertant cells which are an extraordinary tool to study the interaction of cellular genes with the oncoprotein V-Fos. One of these retroviruses produces paralysis and neurological lesions similar to those produced by the AIDS virus. Jolicoeur has identified and cloned a defective retrovirus responsible for MAIDS (murine acquired immunodeficiency syndrome).
Recently his laboratory has developed a novel model of Aids in mice expressing HIV-1.
Dr. John Jonas
Affiliation: McGill University
Keywords: Physical metallurgy, mechanical metallurgy, deformation processing
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Prof. Jonas is Canada's foremost researcher on the hot deformation of steels. An internationally acknowledged leader in research in this area, he has published over 500 scientific papers, co-authored three books on the topic, and is currently Birks Professor of Metallurgy at McGill. He is a pioneer in the application of mathematical modelling to hot deformation of metals and one of the first to demonstrate that results obtained in the lab could be used in the design of industrial rolling processes. Consequently, most Canadian steel companies and indeed many others around the world use the results of Prof. Jonas' research in the design of their rolling schedules.
Alister Jones
Affiliation: None
Keywords: Spectroscopy, aeronomy, magnetosphere, aurora
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Dr. A. Vallance Jones, is now retired from his position as a Principal Research Officer with the National Research Council which he joined in 1968. Previously, he was a Professor of Physics at the University of Saskatchewan. He received his Ph.D. in 1950 from the University of Cambridge, his M.Sc. and B.Sc. in 1946 and 1945 respectively from the University of New Zealand. He is a fellow of the Royal Society of Canada. His work has been primarily in the spectroscopy of aurora and airglow and in other studies of aurora by optical methods. He is a past associate editor (Space Science and Aeronomy) of the Canadian Journal of physics and past Chairman of the Aeronomy Division of the International Association of Geomagnetism and Aeronomy. He also served for a number of years as secretary of the NSERC Grant Selection Committee on Space Science and Astronomy. He is the author of over 100 scientific papers and books on aurora borealis.
Dr. David Jones
Affiliation: The University of British Columbia
Keywords: Evolution, circulation, metabolism, behaviour
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Dr. Jones is a leading international authority on cardiovascular dynamics in lower vertebrates and on the control of breathing during diving in all vertebrate groups. His early studies changed concepts of blood distribution in the anuran ventricle and established a role for the conus arteriosus. He pioneered the application of wave transmission theory to avian and amphibian cardiovascular systems. He provided the first demonstration of baroreceptors in non-mammalian vertebrates and is a world authority on intravascular receptors in lower vertebrates. He has published over 80 scientific papers and organized several international symposia.
G. Melvill Jones
Affiliation: University of Calgary
Keywords: Neuroscience, spatial orientation, locomotion, vesitbular physiology, neural plasticity
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Physiologist and test pilot, Melvill Jones won recognition for his pioneer analyses of bail-out stresses, pilot disorientation, and performance in long-duration flight. Later came his classical studies on (1) vestibular dynamics, (2) the vestibulo-ocular reflex (which stabilizes the retinal image during head movement), (3) human responses to vertical acceleration, and (4) the neural programmes involved in landing from a jump, and in dancing and running. Research on neural plasticity has been stimulated by his discovery that the vestibulo-ocular reflex attenuates, and eventually reverses, in volunteers wearing reversed-vision spectacles for several weeks. His advice and research collaboration have significantly influenced U.S. man-in-space programmes.
John Bryan Jones
Affiliation: University of Toronto
Keywords: Biocatalysis, enzymes, protein engineering
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Jones has made major contributions to a variety of areas of organic and bioorganic chemistry. These comprise the synthesis and conformational analysis of steroids; the mechanism and specificity of the enzymes of steroid metabolism and the effect of micellar aggregation on such metabolism; the mechanism of action of carcinogenic lactones; the structure and function of chymotrypsin; the utilization of enzymes in organic syntheses. It is in this last area that he is currently most active and Jones' pioneering work has made him a world leader in the use of enzymes as chiral catalysts for asymmetric synthesis.
Dr. R. Norman Jones
Affiliation: University of Alberta
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André Joyal
Affiliation: Université du Québec à Montréal
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André Joyal has made profound contributions to four branches of mathematics using elegant categorical methods. He revolutionalized 'combinatorics' by letting coefficients of power series be finite sets. In 'topology', he replaced spaces by locales, dispensing with Euclid's points, and developed a categorical treatment of "braids", preparing for an attack on "knots" and "strings" in physics. In 'algebra', he significantly improved and generalized Grothendieck's Galois theory. In 'logic', he pioneered categorical models of type theory and is linked with the American philosopher in "Kripke-Joyal semantics" for intuitionistic higher order logic.
Dr. Harold Kalant
Affiliation: University of Toronto
Keywords: Addiction, behavioural pharmacology, neuropharmacology
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HAROLD KALANT, Department of Pharmacology, University of Toronto, since 1959 has studied the biological effects of drugs of dependence in the rat. He has demonstrated the acute and chronic effects of alcohol on behaviour, tolerance, dependence, learning ability, metabolism, and functional and organic change. Chronic administration produces a fatty liver, prone to the necrosis seen in man prior to cirrhosis. Necrosis may be aborted by suppressing the thyroid with propyl thiouracil - a possible treatment for human cirrhosis. His more recent work has contributed major new insights into the interaction of pharmacolocical factors with environmental, behavioral and neurobiological mechanisms in the production of drug tolerance and dependence. His work with alcohol and other drugs has earned him international recognition; he has served on several foreign advisory bodies and committees of the World Health Organization. He is co-author or editor of seventeen books concerning drug use, one of which has French and Norwegian editions. He was inducted as a Member into the Order of Canada.
Dr. John Kalbfleisch
Affiliation: UM School of Public Health
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JOHN DAVID KALBFLEISCH has made deep and important contributions to several areas of statistics. His earliest work was on the theoretical foundations of statistical inference. His most extensive contributions, however, are in the relatively new areas of survival analysis and life history analysis, where he has done seminal work since the early 1970's. His 1980 book with Ross Prentice on survival analysis is still the most influential in the field. It and Dr. Kalbfleisch's research articles have had a major impact both on statistics and on subjects such as economics, medicine and sociology, where survival and life history analysis are widely used.
Dr. Werner Kalow
Affiliation: University of Toronto
Keywords: Pharmacogenetics
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The introduction of muscle-relaxing drugs revolutionized surgery, but a few patients were curiously slow to resume breathing after their operations. Werner Kalow solved that puzzle when he found that the patients had a hidden abnormality: their blood contained the enzyme that usually destroys the drug, but in an atypical form. Kalow worked out the genetics of the trait, and he and others found further examples of the situation. He thus established pharmacogenetics as a new branch of medical science; he wrote the first book about it; and he provided the first clear example of the principle that an enzyme-deficiency disease of hereditary origin may be characterized by alteration rather than absence of the enzyme.
Dr. Musa Kamal
Affiliation: McGill University
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Musa Kamal is one of the leading researchers in the polymer processing field. During the last 30 years, Kamal has carried out pioneering research to understand and control plastics manufacturing processes and to optimize and improve the properties of plastics. His important contributions in computer simulation and control of injection and blow molding, and elucidation and manipulation of microstructure of plastics, including blends and composites, are widely used and recognized internationally. He has co-edited three monographs, co-authored over 170 scientific publications, obtained six U.S. patents, and organized major international conferences, while maintaining strong links with industry.
Richard Kane
Affiliation: Western University
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Richard Kane is one of the leading experts on the important area of algebraic topology which studies Hopf spaces. The major achievement in this subject, which originates with work of Heinz Hopf over fifty years ago, is the cohomological classification of finite Hopf spaces. This classification is largely due to J.P. Lin and to Professor Kane, and culminates in their proof of the Loopspace Conjecture, which is the most impressive piece of work in the subject.
Undoubtedly the major work in this area is Kane's recent book in which he recounts the details of this classification - a major triumph of modern mathematics and the subject of numerous articles and research papers by Kane over the past decade.
The techniques which Kane introduced during this work have found plentiful use in other areas of algebraic topology.
Dr. Chil-Yong Kang
Affiliation: Western University
Keywords: Virology, biotechnology, infectious diseases, vaccine, molecular biology, COVID-19, Covid-19, corona virus
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Dr. Kang has made outstanding contributions to our understanding of the replication strategies of negative stranded RNA viruses. In particular, his work on molecular characterization of defective interfering virions and the mechanism of homologous viral interference has laid a firm foundation for the development of therapeutic agents to control viral infections in the future. Dr. Kang's earlier discovery of cellular reverse transcriptase, undertaken as a post-doctoral fellow with Dr. Howard Temin, proved this enzyme is a universal entity. Furthermore, Dr. Kang's recent success in developing gene expression systems for cloned foreign genes makes him one of the leading biotechnologists in the world.
Dr. Kuo Kao
Affiliation: National Research Council
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Dr. Kao has led the world in solving central problems in artificial hybridization of plants using tissue culture. His highly innovative contributions have helped Canada to achieve a preeminent international reputation in this field. He pioneered the production of cell cultures from protoplasts and was first to fuse protoplasts using polyethylene glycol. His fusion method is now standard for plant, animal and bacterial cells. Dr. Kao developed the first inter-family somatic hybrid cultures (soybean and tobacco) and demonstrated activity of both parental genomes. Dr. Kao also played a central role in develoloing haploid barley plants through both embryo and anther culture.
Dr. Raymond Kapral
Affiliation: University of Toronto
Keywords: Statistical mechanics, quantum mechanics
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Raymond Kapral of the Department of Chemistry, University of Toronto, has made signfficant contributions to the theory of condensed-phase reaction dynamics. He developed microscopic descriptions, based on kinetic theory and molecular dynamics, for the role that the solvent plays in determining the outcome of a reactive event in solution. He has devised new methods for the study of complex, far-from-equilibrium, reacting media and has investigated fundamental issues related to the emergence of macroscopic chemical patterns from the microscopic and mesoscopic scales. He has explored the new kinds of chemistry that occurs on small scales in clusters and condensed media.
Dr. Gabriel Karl
Affiliation: University of Guelph
Keywords: Quarks, atoms, nuclei, quantum mechanics
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Gabriel Karl has made outstanding contributions to theoretical high energy physics, and his work has been widely recognized internationally. His deep physical insight and his knowledge of mathematical methods led to the quark model of baryon resonances, based on quantum chromo-dynamics, which has been enormously successful in describing experimental results. His research is characterized by real originality, and also an ability to combine basic ideas from different fields as in the predictions of a new effect - 'neutron optical activity'. Continually he is invited to visit and address the staff of International Laboratories in his field. For two years he was the chairman of NSERC's High Energy Physics Committee.
Dr. Kenneth Kasha
Affiliation: University of Guelph
Keywords: Haploidy (plants), transformation (gene), cytogenetics, microspore culture, biotechnology (of crops)
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Dr. K.J. Kasha has made some fundamentally important contributions to crop science, including the development of a method for making haploid barley plants from immature embryos. This technique has been extremely useful in helping to understand mechanisms controlling chromosome replication and elimination and in the regulation of gene expression. It has also been useful in a practical sense in introducing new genes into barley that have improved both feed and malting properties. The impact of this work has brought him international and national recognition, including an honorary degree and the award of the Ernest C. Manning Award for outstanding innovation by a Canadian. He has held important offices in Canadian Societies and was the founding Director of the Guelph/Waterloo Biotechnology Centre.
Dr. Morris Kates
Affiliation: University of Ottawa
Keywords: Lipids, metabolism, biosynthesis, microorganisms, plants
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Dr. Morris Kates received his Ph.D. degree from the University of Toronto in 1948. His doctoral thesis described the first successful synthesis of a natural phospholipid, dipalmitoyl lecithin. Since 1951 when he joined the Division of Biosciences, National Research Council, and later in 1968 when he transferred to the Dept. of Biochemistry, University of Ottawa, his investigations dealt with the chemistry, biosynthesis and metabolism of lipids in plants and microorganisms. He discovered in membranes of extremely halophilic bacteria a new class of lipids derived from a phytanyl diether of glycerol. Dr. Kates has published two hundred and ten research papers and twenty-one review articles on lipolytic enzymes, and plant and bacterial lipids, and has established himself as one of the
leading investigators in this field.
Dr. Leon Katz
Affiliation: University of Saskatchewan
Keywords: General physics
Chaos
Fractals
Nuclear physics
Thermodynamics
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