Bob Hodges is Canada's premier synthetic-peptide chemist and is internationally recognized as being at the leading edge of peptide chemistry. Using synthetic peptides he has made major contributions in our understanding the structure of tropomyosin and in identifying the active site regions of several muscle proteins such as troponin-I as well as regions of interaction between the various members of the troponin-tropomyosin complex. His studies with the calcium binding peptide analogs of the troponin C/calmoduli calcium binding sites have given clear-cut chemical rationales as to the metal specificity of these sites and why some are high-affinity and others are low-affinity. Dr. Hodges has also expanded into new and promising areas such as the technology and production of antibodies to proteins from synthetic peptide antigens. In addition, he has provided a very valuable resource to other investigators in Canada requiring the design and synthesis of tailor-made peptides through the Alberta Peptide Institute which he directs. His international stature is also indicated by the regularity with which he serves as a key-note speaker in symposia dealing with peptide chemistry, calcium binding proteins and HPLC chromatography, and his extensive and significant bibliography of some 152 publications.