Garry Clarke, a notably sound geophysicist with a deep respect for thermodynamics, has become an international authority on thermal regimes of glaciers, and the effect of temperature on glacier flow, including the phenomenon of glacier surging. He is unquestionably Canada's leading scientist in these fields. Thoroughly adept at mathematical modeling and in the theoretical aspects of glaciology, he is equally at home both in instrumentation and in field work on the ice itself. He is an effective communicator with scientists in neighbouring disciplines, able to grasp their problems and apply his expertise to the solutions.

Dr. Yves Clermont, an outstanding microscopist, has reached international repute on the basis of his work on the testis. At scientific meetings dealing with male reproduction in the United States and Europe, he is usually the one asked to describe the structure of the testis and the dynamics of sperm cell formation. Indeed, as a result of work by his group, the knowledge of the seminiferous epithelium has reached a degree of sophistication which is rarely found in morphological studies. His teaching is equally outstanding. The clarity of his lectures, the artistry of his drawings on the blackboard and his relaxed presentations make him one of the best loved teachers at McGill University.

Ronald Martin Clowes has distinguished himself as a dynamic explorer of the Earth's crust, pioneering the application of sophisticated seismic methods to unravel the complex underground structure of Canada's western continental margin. Through his personal research, and more lately through his direction and scientific leadership of "LITHOPROBE", Canada's largest Earth Science program, Ron Clowes has made lasting contributions to Canadian Earth Sciences. These contributions have already brought him national and international recognition.

Professor John S. Colter has, within the past twenty years, achieved an international reputation as an investigator in the fields of Virology and Cancer Research, with over 60 published papers to his credit. Professor Colter has been active in editorial work with several publications. He has been on the Executive of the Canadian Biochemical Society, and is now chairman of the N.R.C.'s National Committee for the International Union of Biochemistry. Professor Colter has attracted an outstanding group of young biochemists, in a variety of fields, to the Department at the University of Alberta. The Department has become well-known for its excellent programs in graduate training and research.

Alain Connes is one of the world's leading mathematicians. His early work - a critical part of it carried out in this country - revolutionized the study of operator algebras. Not only did it solve the central problem in the subject, open since the work of Murray and von Neumann forty years earlier, but it carried the subject to a state of maturity which could not even have been imagined. In the last fifteen years, Dr. Connes has gone far towards revolutionizing the rest of mathematics as well - and, with it, physics. His non-commutative geometry - building on an operator algebra framework - may turn out to be this century's most profound mathematical discovery.

Professor Cook is recognized as one of the world's foremost contributors to the theory of computational complexity. The field is concerned with developing and analyzing algorithms for solving problems faster, and proving lower bounds for the time required to solve certain problems no matter what algorithm is used. Cook has shown that a large number of combinatorial problems can be classified into a group now called NP complete. For these problems no good algorithm now exists, and Cook showed that if a good algorithm exists for any one of the group, it does for them all. His work has already inspired over 100 papers by other researchers. Much of Cook's current work is centered around proving that no good algorithm exists for one (and thus all) of these problems. This question is now regarded as the most important question in the theory of computation, and a very important open question in mathematics generally.

Paul B. Corkum, Senior Scientist in the Laser Physics Division of the Steacie Institute of the National Research Council of Canada is considered to be Canada's 'foremost' laser scientist. His innovative contributions to this young fastly growing discipline have won him international praise and recognition for seminal work on three fronts. Corkum's outstanding work on the interaction of atoms and molecules with intense laser radiation, and on applications of ultrafast laser techniques to chemical, solid state and plasma physics is in the forefront of laser research worldwide. He continues steadfastly in his innovative pursuits, and is currently defining new areas of ultrafast research. The impact of this work is growing coontinuously, thus enhancing Corkum' s reputation as a world leader in laser science.

In the short space of ten years, Dr. Cossins has established an enviable international reputation for productive research in the fields of amino acid metabolism and the role of folic acid derivatives in transmethylation and other types of one-carbon metabolism in the lower and higher plants. He or his associates have presented papers at two International Congresses and two International Symposia in the last two years. Dr. Cossins is an excellent teacher and counsellor of students. He is an active member in the affairs of several botanical and biochemical societies and is currently serving as an Associate Editor of the Canadian Journal of Botany. He is a fine scientist and one of the leading plant biochemists in Canada, today.

Ronald Coutts is one of Canada's leading pharmaceutical chemists. He has won an international reputation for the application of sophisticated physical and analytical techniques to studies of drug metabolism and toxicology. He is a Fellow of the Royal Institute of Chemistry and of the Chemical Institute of Canada, and was awarded the D.Sc. of the University of Strathclyde in recognition of his outstanding contributions. Professor Coutts has published nearly 100 research papers and many reviews. He has been in demand as a visiting professor and as a lecturer at international meetings. He is a superb teacher and has attracted a group of graduate students and post- doctoral fellows. Dr. Coutts has been a member of several MRC committees and is active in faculty administrationand in the University Faculty Association. At present, Dr. Coutts is especially interested in the biological and medical applications of the methods he has developed. Current research interests are: I. Analysis of drugs, drug metabolites, endogenous amines and amino acids, and environmental chemicals in biological (urine, blood, CSF, brain, etc) and environmental samples, and in foodstuffs. 2. Metabolism of numerous drugs in neonates, adults, elderly patients and animal models; microbial metabolism of various antidepressant drugs, endogenous amines and prodrugs; drug metabolism 'in vitro' using pure human cytochrome P450 isozymes. 3. Identification and effects of inducers and inhibitors of drug metabolism; pharmacologically active metabolites; drug/drug interactions.

Dr. Richard L. Cruess has established and developed the leading basic science laboratory for orthopaedic research in Canada. In addition, to stimulating an interest in research among undergraduate and past graduate students, Dr. Cruess has made important contributions to our basic knowledge of the pathogenesis and pathology of numerous musculoskeletal abnormalities including idiopathic avascular necrosis of the femoral head and the deleterious effects of prolonged administration of corticosteroids on bone and cartilage (a subject in which he is a world renowed authority). He has also investigated metabolic bone disease and lipids in bone with particular respect to Vitamin D and estrogens. Dr. Cruess is currently studying feasibility of transplantation of the epiphyseal (growth) plate in animals using microvascular techniques. His research has been consistently elegant, sophisticated and significant.

A. Claudio CUELLO, Professor, Department of Pharmacology and Therapeutics, McGill University, has made significant contributions to neuroscience and neuropharmacology, developing new techniques for the cellular and subcellular localization of transmitter substances in the peripheral and central nervous system and introducing new concepts in the field. His work has significantly advanced the idea that small peptides can act as transmitter messengers in defined neuronal pathways; that neuron cell dendrites might release neurotransmitters; and that new synaptic contacts in the cerebral cortex of lesioned animals can be generated by the exogenous application of growth factors.