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Dr. David Denhardt
Affiliation: Rutgers University
Keywords: Gene regulation, cancer, molecular biology, cell Biology, signal transduction
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Dr. Denhardt is one of the pioneers in the area of the mechanism of viral replication. He developed one of the first 'in vitro' systems capable of replicating OX 174 viral DNA in the earlier stages of his career. He was the first one to devise techniques for the detection of complementary DNA by simple filtration procedures. With the advent of gene cloning, his DNA-DNA hybridization procedure has come into wide-spread use. He is widely known also for his discoveries in the field of DNA replication. He was the first to show that RNA was used to prime synthesis of nascent DNA in the intact cell. His laboratory is internationally recognized and he is respected in the world science community.
More recent research has focused on how normal cells became metastatic, particularly the role of osteopontin in the process. Osteopontin is a cytokine and bone matrix protein that is required for some forms of bone turnover. Other studies have uncovered aspects of how tissue inhibitor of metalloproteineses functions as a tumor suppressor.
Dr. David Dennis
Affiliation: Queen's University
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A dynamic researcher and educator who has elucidated the important metabolic roles of non-green plastids in plants. His research established the occurrence of glycolysis and the pentose phosphate pathway in plastids and demonstrated the importance of these pathways to the supply of carbon compounds for fat synthesis. Through diligent effort he has established that the isozymes in the plastid have regulatory properties that are distinctively different from their cytoplasmic counterparts. He is actively investigating the genetic relationships of the various isozymes and the import of one of the isozymes into the plastid. Through his extensive work he has established the importance of compartmentation in the regulation of metabolism in plants.
Dr. Douglas Derry
Affiliation: The University of British Columbia
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Mr. Pierre Deslongchamps
Affiliation: Université de Sherbrooke
Keywords: Chimie organique, synthèse, mécanisme réactionnel, effets stéréoélectroniques, chimie médicinale
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Pierre Deslongchamps est, au témoignage de nombreux collègues, un des plus brillants chimistes de la jeune génération. L'attestation du Professeur R.B. Woodward, de Harvard, est particulièrement éloquente à ce sujet. Le talent exceptionnel, l'imagination créatrice et l'activité débordante de M. Deslongchamps ont attiré dans son laboratoire une équipe enthousiaste de jeunes chercheurs. Il a été l'objet de distinctions signalées, dont la Bourse commémorative E.W.R. Steacie, et le Prix scientifique du Québec en 1971. M. Deslongchamps est encore jeune, mais son succès n'en est que plus exceptionnel.
André DesMarais
Affiliation: Industrie Canada
Keywords: Nutrition, endocrinologie, histologie, système nerveux, système cardio-vasculaire
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André DesMarais est l'auteur de plus de 40 articles originaux dans le domaine de l'endocrinologie, surtout en relation avec la thermogénèse. Sa réputation a depuis longtemps dépassé les frontières de son pays : en 1959, par exemple, il était invité à présenter les résultats de ses recherches sur le rôle de la thyroïde au froid à un symposium international sur le froid, tenu à Buenos Aires, en Argentine.
Dr. LLoyd Dickie
Affiliation: Fisheries and Oceans Canada
Keywords: Synecology, biomass size-spectrum, production
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Dickie's interests are primarily in marine ecology and fisheries. In association with a mathematician (J.E. Paloheimo) he has developed production equations for marine food chains, using physiological and behavioural characteristics. In 1968 he was invited to give a special lecture at the International Council for the Exploration of the Sea, meeting in Copenhagen (the only invited lecture). In 1970 he was invited lecturer on Food Chains at the Centennial celebrations of the American Fisheries Society. Currently he is co-author (with R.W. Stewart) of the Science Council Report on Marine Science & Technology in Canada.
Dr. Erwin Diener
Affiliation: University of Alberta
Keywords: Immunoregulation, immunological tolerance, autoimmunity, immunophylogeny
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Diener's first momentous discovery in relation to the phylogenetic development of lymphoid tissue was that 'Monotrems' represented the missing evolutionary link between 'Amphibians' and 'modern' mammals. His international reputation rests on the (i) functional dissection of immune triggering mechanisms and (ii) induction of antigen specific unresponsiveness. Diener predicted and confirmed experimentally that polymeric antigens and linear antigen-antibody complexes had the capacity to 'switch off' the immune responsiveness. He further demonstrated that an antigen's tolerogenic potential rests on properties of its carrier rather than on its binding avidity for antibody and his work suggests a re-evaluation of current theories on unresponsiveness to 'self'. His contributions have been recognized as classical concepts and are cited in basic textbooks on Immunology.
Prof. Walter Dilger
Affiliation: University of Calgary
Keywords: Concrete structures, bridges, time-dependent effects, temperature effects, punching shear
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Walter Dilger is Professor of Civil Engineering at The University of Calgary. Dr. Dilger's original contributions to research on time-dependent and temperature effects in concrete and composite structures, ductility of reinforced concrete and design of partially prestressed concrete members has led to a better understanding and prediction of structural performance. He is coinventor of the stud shear reinforcement for flat slab, which is used in North America, Europe and Australia. His designs in bridge engineering have won several international awards. He received the 1991 Killam Memorial Prize for research Engineering.
Dr. Lawrence Dill
Affiliation: Simon Fraser University
Keywords: Behavioural ecology, marine biology, ecology
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Lawrence Dill is Canada's most distinguished scholar and intellectual leader in the field of Behavioral Ecology. He has published pioneering research pertaining to foraging, territorial, predator avoidance, and other types of behavior, and has developed optimality models which have been tested in the laboratory and in the field. These research results have influenced other areas of ecology, especially the study of population dynamics and community structure. Dill's research has contributed to the modern resurgence of evolutionary thinking in behavioral biology, psychology, medicine, and other areas.
Dr. Peter Dillon
Affiliation: Trent University
Keywords: Biogeochemistry, environment, aquatic, carbon, acidification
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Dr. Dillon is one of the world's most active researchers in the field of aquatic biogeochemistry. His work was instrumental in demonstrating the key role of water renewal in the relationship between inputs of pollutants to lakes and the resulting concentrations. This concept is now incorporated in all major pollutant budgets for lakes.
Dillon's studies of the chemistry of lakes in eastern Ontario were instrumental in the establishment of phosphorus control in lake management. He was the first to discover that polluted precipitation was severely acidifying lakes in areas of Ontario remote from local point sources.
Dr. John Dirks
Affiliation: University of Toronto
Keywords: Global health, Gairdner Foundation - biomedical awards
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Using the micropuncture technique, which he introduced into Canada, Dr. Dirks has made major contributions to our knowledge of the mechanisms of action of diuretics, and on the transport of calcium by the kidney. He studied magnesium transport in terms of segmental nephron function, and more recently has thrown light on sodium transport by the kidney in heart failure. This distinguished and creative research career has brought distinction to Canada in this field. In his capacity as President of the Canadian Society for Clinical Investigation, Dr. Dirks has provided outstanding leadership by his intervention on behalf of medical research in Canada.
Dr. Vlastimil Dlab
Affiliation: Carleton University
Keywords: Representation theory of algebras
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Dr. Dlab's mathematical work is devoted to algebra. His first interest was the theory of infinite abelian groups. He evolved later to the study of endomorphisms of abelian groups, with some incursions into the theory of ordered groups and universal algebras. His most significant work is the one done recently in collaboration with C. Ringel. It is a study of perfect rings, universal rings, balanced rings, their structure and representation theory.
Edward Donaldson
Affiliation: Fisheries and Oceans Canada, The University of British Columbia
Keywords: Aquaculture, fish endocrinology, stress, reproduction, sex control, growth
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E.M.Donaldson, Research Scientist in the West Vancouver Laboratory, Department of Fisheries and Oceans, studies reproduction, growth and genetics of fishes - particularly salmon. Research on reproductive hormones has contributed methods used to induce breeding and control the timing of egg production; growth hormone studies show potential for the development of larger fish, while the genetical studies permit the production of populations of either males or females - an important advance for both industry and fish culturist. Dr. Donaldson is active in fisheries research planning in Canada, as well as several developing countries through CIDA and the IDRC.
Mark Donelan
Affiliation: University of Miami
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Mark Donelan, School of Marine and Atmospheric Science, University of Miami, is internationally recognized for his research on air-sea interaction, especially in the field of ocean surface waves. Among his many contributions are the determmation of the directional spectrum of wind generated waves, his recognition of the relationship of quasi-periodic wave breaking to linear dispersion theory and his demonstration that the vertical profile of turbulent dissipation differs markedly from the law found near solid boundaries. The problems he tackles are important and his papers are distinguished by their originality and clarity. He provides outstanding leadership in collaborative field investigations and has contributed extensively to international scientific planning and collaboration.
Dr. W. Doolittle
Affiliation: Dalhousie University
Keywords: Molecular evolution, genomics, metagenomics, philosophy of biology
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Dr. Doolittle, Dalhousie University, studies biological evolution at molecular and cellular levels. He introduced the influential concept of 'selfish DNA', and made seminal analyses of the intron/exon theory of the gene. His studies of the molecular biology of the cyanobacteria (blue-green algae) provided crucial experimental support for the endosymbiotic theory of the origin of chloroplasts. He is Director of the Evolutionary Biology Program for the Canadian Institute for Advanced Research which is now studying the molecular genetics of archaebacteria.
Roger Downer
Affiliation: University of Limerick
Keywords: Third level education, research, sustainability, global poverty
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Roger Downer has directed his research towards an increased understanding of insect bio-chemistry and physiology. He has concentrated on the biochemistry and transport of lipids, the regulation and metabolism of carbohydrates, and the action of biogenic amines in trans-membrane signalling mechanisms. He has successfully challenged established dogmas, and developed novel experimental procedures and technologies to resolve critical questions. His approach is characterized and driven by an innate curiosity and excitement about 'how insects work'. He is alert to the practical applications of his discoveries, and has built strong industrial links. He is a role model for young Canadian scientists.
Dr. R. Keith Downey
Affiliation: Agriculture and Agrifood Canada
Keywords: Brassica oilseeds, plant breeding, biotechnology
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Breeder or co-breeder of Beaver alfalfa and 7 varieties of rapeseed. Public Service award 1968 for rapeseed studies; American Oil Chemists 1963 Bond Medal for biosynthesis of rapeseed fatty acids; Agricultural Institute of Canada Grindley Medal 1973 for outstanding contribution to agriculture; Royal Bank of Canada award 1975 for outstanding contribution to human welfare and the common good. Published over 30 scientific papers and over 50 miscellaneous publications on rapeseed. Dr. Downey made the 'break through' in genetically modifying rapeseed to eliminate erucic acid from rapeseed oil. He also developed the 'half seed' technique, permitting analysis of half the seed while growing the other half, thereby greatly expediting genetic advance. He was a team member in the interpretation of the biochemistry of fatty acid synthesis in rapeseed and was a leader in the development of rapeseed strains nearly devoid of the goitrogenic factors called glucosinolates.
Dr. Gordon Drake
Affiliation: University of Windsor
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Gordon Drake has made important contributions to the field of Atomic Physics. In particular he gave the first correct evaluation of the radiative decay rate of metastable helium atoms. He also developed a unified relativistic treatment of radiative transitions in helium-like ions and developed a new method for measuring the Lamb shift. This new method allowed the very accurate measurement of lifetimes of excited states of the hydrogen atom.
Prof. Aleksis Dreimanis
Affiliation:
Keywords: Subglacial sedimentation, glacial tectonics, late Pleistocene stratigraphy, glacial indicator tracing
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Dr Dreimanis enjoys an international reputation for his studies in the stratigraphy and physical characteristics of the glacial deposits of southern Ontario. The results of this research have provided glacial geologists with a very accurate and detailed account of events during the Wisconsin glaciation in the lower Great Lakes.
Dr Dreimanis has developed and refined several quantitative procedures used to identify glacial deposits and these techniques have become standard methods of analysis in laboratories throughout the world.
Although an expert in glacial stratigraphy, Dr Dreimanis has published some 85 papers on virtually all aspects of glacial geology and geomorphology.
Dr. G. Duff
Affiliation: University of Toronto
Keywords: Differential equations
Mathematical analysis
Applied mathematics
Fluid mechanics
Tidal energy
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G. F. D. Duff is Associate Professor of Mathematics, University of Toronto. He graduated from the University of Toronto in 1948 and received his M.A. degree in 1949 on the basis of a paper published in the 'Canadian Journal of Mathematics"; this is the only time the M.A. has been given in this way at Toronto. He was elected Proctor Fellow at Princeton 1950-1 and received his Ph.D. degree in 1951. In the following year he was Moore Instructor at Massachusetts Institute of Technology and joined the staff at Toronto in 1952. He is now Editor-in-Chief of the "Canadian Journal of Mathematics".
Mr. L.-Paul Dugal
Affiliation:
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Dr. Francis Dullien
Affiliation: University of Waterloo
Keywords: Flow through porous media, air/gas cleaning
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Francis Andrew Leslie Dullien, Professor Emeritus, Department of Chemical Engineering, University of Waterloo, made significant contributions to the areas of fluid transport and structure of porous media. His work in these areas made him internationally renowned. He developed predictive equations for Knudsen and ordinary diffusion based on the kinetic theory of gases as well as phenomenological relations between viscosities and intra-diffusivities of liquids and gases which provided explanation for the formal validity of the Stokes-Einstein relationship for pure liquids and is diagnostic of e.g. prefreezing clusters. Recently he has discovered a new concept of fluid/solid contacting, utilizing penetration of turbulent eddies into stagnant pockets of fluids, permitting very efficient gas cleaning.
Ms. Moira Dunbar
Affiliation: National Defence - Défense nationale
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Moira Dunbar has made studies of the ice of the Canadian Arctic for more than two decades, involving participation in a dozen expeditions. She has also contributed to problems of ice in two winter cruises in the Gulf of St. Lawrence.
Her knowledge of the Russian language and Arctic literature has been put to good use in translations and as a member of a Canadian group visiting Russia.
As a fellow and governor of the Arctic Institute of North America she has written and edited many papers on ice movements and terminology.
Dr. David Dunlop
Affiliation: University of Toronto
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Professor Dunlop has established an international reputation for his work in rock and paleomagnetism. Recognition has come through many invitations to present accounts of his studies at scientific meetings. He has been asked to review state-of-the-art developments in rock and paleomagnetism at two successive meetings of the American Geophysical Union. His list of publications shows him to be an energetic and steadily productive scholar, and his pre-eminence in his chosen field has won for him the award of a Killam Fellowship. In addition he is an excellent teacher, at the undergraduate as well as the graduate level. In a broader context, the high regard in which his geophysical colleagues hold him has been demonstrated by his election as President of the Canadian Geophysical Union and to Fellowship in the American Geophysical Union. He was recently awarded the Louis Néel Medal of the European Geophysical Society and the Tuzo Wilson Medal of the Canadian Geophysical Union.