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Dr. Shoukat Dedhar
Affiliation: The University of British Columbia
Keywords: Cancer, cell adhesion, translational research, biochemistry
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DEDHAR, Shoukat, Department of Biochemistry and Molecular Biology, The University of British Columbia
Shoukat Dedhar’s pioneering work in the field of cell adhesion have uncovered the molecular basis of how cells in the body adhere to the surrounding matrix and how cell adhesion regulates fundamental aspects of cellular physiology. His discovery of Integrin-Linked Kinase has generated a large body of work which has demonstrated fundamental roles of this protein in normal tissue function and pathologies such as cardiovascular dysfunction, renal failure, and cancer.
Dr. Paul Frankland
Affiliation: University of Toronto
Keywords: memory, forgetting, plasticity, neurogenesis
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FRANKLAND, Paul - Neurosciences & Mental Health, The Hospital for Sick Children Research Institute, University of Toronto
Professor Paul Frankland is recognized as a world leader in memory research. His studies have uncovered the neurobiological processes underlying how we learn, remember and, in some cases, forget. Knowledge gained from Prof. Frankland’s research provides a foundation for the development of better treatments for memory-related disorders.
Dr. Sara Iverson
Affiliation: Dalhousie University
Keywords: Lipid metabolism, fatty acid signatures, animal movemnet, aquatic ecosystem structure, ocean governance
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IVERSON, Sara - Department of Biology, Dalhousie University
Sara Iverson’s interdisciplinary and ground-breaking research has advanced the understanding of marine animal physiological ecology; roles of fat in mammalian reproduction, survival and life history strategies; and marine animal movement and foraging ecology. She leads the global Ocean Tracking Network, the world’s foremost aquatic animal tracking network and now a Canadian National Research Facility, which is revolutionizing the way aquatic life is viewed, understood and governed under increasing environmental change.
Dr. Prabhat Jha
Affiliation: University of Toronto
Keywords: tobacco, epidemiology, economics, mortality statistics, COVID-19, Covid-19, corona virus
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JHA, Prabat - Centre for Global Health Research and Dalla Lana School of Public Health, University of Toronto
Prabhat Jha has led pioneering epidemiological and economic studies which have established tobacco as the most important contributor to premature adult mortality and identified taxation as the most effective means to reduce tobacco consumption (enabling the first global treaty on health). Jha has done outstanding research on the reliable assessment of causes of death including the Million Death Study of a random sample of all deaths in India since 2001.
Dr. Sheena Josselyn
Affiliation: University of Toronto
Keywords: memory, neuroscience, optogenetics, circuits
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JOSSELYN, Sheena - Neurosciences & Mental Health, The Hospital for Sick Children Research Institute, University of Toronto
Professor Sheena Josselyn is a world leader in investigating how the brain encodes, stores and uses information. Her studies break new ground and have changed the way the field of neuroscience views
memory. The fundamental insights gained by Prof. Josselyn’s research into basic memory processes in
rodents may translate into superior ways of treating - or even preventing - devastating human brain disorders.
Dr. Alejandro Marangoni
Affiliation: University of Guelph
Keywords: Lipids, Nanostructure, Crystallization, Microstructure, Triglycerides, Organogels, Nutrition
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Dr. Alejandro G. Marangoni is a Professor and Tier I Canada Research Chair in Food, Health and Aging at the University of Guelph, Canada. His work concentrates on the physical properties of food materials in foods, cosmetics and biolubricants, with particular emphasis on sustainability, preservation of biodiversity and health. With an H-index of 82, i-index of 380 and over 25,500 citations of his work, he has published over 400 refereed research articles, 90 book chapters, 18 books, and over 40 patents. He is the recipient of the 2013 AOCS Stephen Chang award, the 2014 IFT Chang Award in Lipid Science, the 2014 AOCS Supelco/Nicholas Pelick Award, the 2015 ISF Kaufmann Medal, the 2017 AOCS Alton E. Bailey Medal, and the 2019 European Lipid Technology Award from EuroFed Lipids. Marangoni is a fellow of the American Oil Chemists’ Society, the Institute of Food Technologists and the Royal Society of Chemistry (U.K.). He is the Editor in Chief of both Current Opinion and Current Research in Food Science. Dr. Marangoni has also founded and commercialized 3 major technology platforms with global reach. Dr. Marangoni was honored as one of the 10 most influential Hispanic Canadians in 2012, a Fellow of the Royal Society of Canada in 2018, and an Officer of the Order of Canada in 2021.
Dr. Ian Meinertzhagen
Affiliation: Dalhousie University
Keywords: connectome, Drosophila
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MEINERTZHAGEN, Ian - Department of Psychology and Neuroscience, Dalhousie University
Ian Meinertzhagen is a pioneer in connectomics, the comprehensive mapping of brain networks. Internationally acclaimed
for research on simple nervous systems his work reveals circuit models for all brains. In Drosophila he has identified
neurons for motion vision. Meinertzhagen’s studies of photoreceptor axon growth were critical for the then nascent
field of developmental neuroscience. He showed that circuits are influenced by experience, refuting a prevailing
orthodoxy that insect brains are hard-wired.
MEINERTZHAGEN, Ian - Département de psychologie et neuroscience, Université Dalhousie
Ian Meinertzhagen est un pionnier de la connectomique, la cartographie complète des réseaux cérébraux. Acclamé
internationalement pour ses recherches sur les systèmes nerveux simples, son travail révèle des modèles
de circuits pour tous les cerveaux. Chez la drosophile, il a identifié des neurones pour la vision du
mouvement. Les études de Meinertzhagen sur la croissance des axones des photorécepteurs étaient
essentielles pour le domaine alors naissant des neurosciences du développement. Il a montré que les
circuits sont influencés par l'expérience, réfutant une orthodoxie dominante selon laquelle les cerveaux
d'insectes sont câblés.
Dr. Stephen Michnick
Affiliation: Université de Montréal
Keywords: Systems Biology, Genomics, Biological Networks, Signal Transduction, Protein Engineering
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MICHNICK, Stephen - Department of Biochemistry, Université de Montréal
Stephen Michnick has pioneered techniques and has made several discoveries in the field of molecular systems biology, the study of how ensembles of genes and their product proteins interact, determining the structures and behaviors of living cells. His methods provide spatiotemporal maps of the interactions among the thousands of proteins that make up a living cell; information that is being exploited to discover the molecular bases of normal physiological processes and the means to identify and develop strategies to correct pathological states of cells.
Stephen Michnick a mis de l’avant des techniques innovatrices et a fait plusieurs découvertes dans le domaine de la biologie moléculaire systémique, qui explore comment les ensembles de gènes et leurs produits intéragissent, ce qui détermine les structures et le fonctionnement des cellules vivantes. Les méthodes appliquées dans son laboratoire tracent des cartes spatio-temporelles des interactions entre les milliers de protéines constituant la cellule vivante; de l’information qui est exploitée pour établir les fondements moléculaires des procédés physiologiques normaux, mais aussi qui permet d’identifier et de développer des stratégies pour corriger les états pathologiques des cellules.
Dr. Patricia O'Campo
Affiliation: University of Toronto
Keywords: epidemiology, health inequalities, women's health, COVID-19, Covid-19, Corona virus
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O'CAMPO, Patricia - Centre for Urban Health Solutions, University of Toronto
Dr. Patricia O’Campo is an internationally renowned Social Epidemiologist whose research focuses on the health impacts of complex urban social problems experienced by low-income populations. Through her scholarship over the past 25 years, dedicated partnerships with affected communities, and leadership at a large multi-disciplinary health research centre for over a decade, she has advanced methodologies and generated strong evidence for effective solutions to reduce urban health disparities.
Dr. Beverley Orser
Affiliation: University of Toronto
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ORSER, Beverley - Department of Anesthesia and Physiology, University of Toronto
Beverley Orser first identified how general anesthetics cause memory deficits in adults that persist long after the drugs are eliminated from the body. Her landmark papers demonstrated the cause: increased activity of extrasynaptic inhibitory neural receptors. These receptors are targets for anesthetics and other neurodepressive drugs, and, when activated, can impair memory. Her studies have fundamentally advanced our understanding of the neurobiology underlying general anesthesia and have improved patient care.
Dr. Christopher Overall
Affiliation: The University of British Columbia
Keywords: proteases & inhibitors; matrix metalloproteinases (MMP); proteomics; innate immunity; inflammation
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OVERALL, Christopher - Department of Oral Biological & Medical Sciences, The University of British Columbia
Professor Christopher Overall was appointed a Tier 1 Canada Research Chair in Protease Proteomics and Systems Biology (2001-2022) and a Senior Fellow of the Freiburg Institute of Advanced Studies, Albert-Ludwigs Universität Freiburg, Germany (2010–2013), where he is now an Honorary Professor (2014–). He was inducted as a fellow into the Royal Society of Canada, Academy of Science in 2018. He is best known for his development of proteomic methodology for the discovery of protease substrates in vivo, thereby establishing the field of degradomics. He has used these techniques to reveal new biological roles for proteases in immunity and disease, most recently in the COVID-19 pandemic by SARS-CoV-2 proteases, as well as two new molecular correctors to cure MALT1 protease deficiency in a primary immunodeficiency. By generating clinically relevant insights into how proteases dampen disease-fighting defense systems involved in inflammation and immunodeficiency, degradomics has revealed an unexplored layer of complexity in the hierarchy of cell and immune regulation, greatly adding to our understanding of protease function and drug targeting.
Dr. Overall completed his B.D.S., Honours Science and Master’s degrees at the University of Adelaide, South Australia; his Ph.D. in Biochemistry at the University of Toronto, Canada; and was an MRC Centennial Fellow in his postdoctoral training with Dr. Michael Smith, Nobel Laureate, Biotechnology Laboratory, UBC. He launched his lab at UBC in 1993, where he is happily entrenched. On sabbatical in 1997 – 1998, he was a Senior Scientist at British Biotech Pharmaceuticals, Oxford, UK, and in 2004 and 2008, a Senior Scientist at the Expert Protease Platform, Centre for Proteomic Drug Discovery, Novartis Pharma, Basel, Switzerland and is now a Creative Destruction Lab Scientist, UBC Sauder School of Business, and a consultant for Genentech, Novartis and several Biotechnology companies. He is a highly cited scientist (305 Career total, with an h-index = 104 and >38,200 citations—including 67 >100 – 199, 27 >200 – 499, 12 >500 – 999, 3 >1,000 – 1,500, and 1>1,650, including 30 high-impact Nature (1), Science (2), Cell and daughter journal (27) papers, most as senior PI. He has disseminated his lab’s findings by > 266 keynote, plenary and invited talks at international and national conferences, and 236 invited seminars at universities, research institutes and companies. He has trained 40 postdoctoral fellows and graduated 14 Ph.D. and 6 M.Sc. students, with 20 now holding academic appointments: 9 are Full Professors (including 2 Department Chairs), 4 are Associate Professors, and 7 are Assist. Professors.
He was elected by his peers to organize and Chair the 2003 Matrix Metalloproteinase (MMP) and 2010 Protease Gordon Research Conferences, and in 2017 he was Co-Chair of the International Proteolysis Society Biannual Meeting, the premier conferences of his fields. He holds influential roles on the executive of > 10 international committees, the most prominent of which was being elected to the Human Proteome Organization (HUPO) Executive Council and to Chair the HUPO Chromosome-centric Human Proteome Project (C-HPP). In 2022 he was invited to attend the “G7 Research Summit on One Health” as UBC’s representative. He is the recipient of numerous awards, e.g., 2006 Killam Faculty Research Prize, Senior Science UBC; 2002 CIHR Researcher of the Year Award; Helmholtz Award (2008); International Proteolysis Society Lifetime Achievement Award (2011); Matrix Biology Society of Australia and New Zealand Barry Preston Award (2012); and the International Association for Dental Research Distinguished Scientist Award (2013). His advances in proteomics have been recognized by the Canadian National Proteomics Network Tony Pawson Award (2014); the Proteomass Scientific Society Award (2017); the highly prestigious 2018 international HUPO Discovery Award in Proteomics Sciences; the 2022 Helmut Holzer Award; and the UBC 2022 John McNeill Excellence in Health Research Mentorship Award. He is an Associate Editor of the Journal of Proteome Research and the Editor of the Annual Human Proteome Project Special Issue of this Journal.
Dr. Guy Sauvageau
Affiliation: Université de Montréal
Keywords: hematopoiesis, stem cells, leukemia
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SAUVAGEAU, Guy - Department of Medicine, Université de Montréal
Guy Sauvageau’s pioneering discoveries bear on the regulation of both normal hematopoietic stem cells (HSCs) and their malignant counterpart, the leukemic stem cells (LSCs). His seminal studies have identified both cellular factors and synthetic molecules capable of modulating HSCs self-renewal and permitting, for the first time, the ex vivo expansion of these cells. His research has had a direct impact on the development of better and safer treatments for leukemia.
Les découvertes pionnières de Guy Sauvageau portent sur la régulation des cellules souches hématopoïétiques normales (CSH) et de leurs homologues malignes, les cellules souches leucémiques (CSL). Ses études fondamentales ont identifié des facteurs cellulaires et des molécules synthétiques capables de moduler l'auto-renouvellement des CSH et de permettre, pour la première fois, l'expansion ex vivo de ces cellules. Ses recherches ont un impact direct sur le traitement de la leucémie.
Dr. Samy Suissa
Affiliation: McGill University
Keywords: pharmacoepidemiology, drug safety, chronic diseases, medical statistics
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SUISSA, Samy - Department of Epidemiology, Biostatistics, and Occupational Health, McGill University
Professor Suissa is an internationally renowned pharmacoepidemiologist who studies the real-world safety of medications. His landmark studies, showing that inhaled corticosteroids prevent asthma deaths, profoundly altered asthma management and lowered asthma mortality worldwide. His work on oral contraceptives and hormone therapy in women, and on Parkinson’s disease, led to safer clinical practice. He heads the Canadian Network for Observational Drug Effect Studies (CNODES), involving over 60
Canadian scientists.
Professeur Suissa est un pharmaco-épidémiologiste reconnu mondialement. Ces études qui ont démontré que les corticostéroïdes inhalés préviennent la mortalité dans l'asthme, ont profondément transformé son traitement, réduisant cette mortalité mondialement. Ses recherches en santé des femmes, contraceptifs oraux et l'hormonothérapie postménopausique, et sur la maladie de Parkinson, ont façonné une pratique clinique sécuritaire. Il dirige le Réseau canadien pour l'étude observationnelle des médicaments (RCEOM), impliquant plus de 60 chercheurs.
Dr. Douglas R Green
Affiliation: St. Jude Children\'s Research Hospital
Keywords: cell death, apoptosis, mitochondria, Immunology
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GREEN, Douglas R - Department of Immunology, St. Jude Children's Research Hospital
Douglas R. Green is an internationally recognized, highly cited scientist who has made seminal contributions to our understanding of cell death and cell survival, especially in cancer and in the immune system. His work has changed how we think about the function of the mitochondria, which not only provide energy to the cell but are also the focus of the “switch” between cellular life and death.
Prof. Uri Ascher
Affiliation: The University of British Columbia
Keywords: Numerical Solution of Differential Equations, Nonlinear Optimization, Inverse Problems, Scientific Computing
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ASCHER, Uri - Department of Computer Science, The University of British Columbia
Uri Ascher has made fundamental contributions to scientific computing and its application in computer graphics, geophysics, image processing, robotics, semiconductors, fluid dynamics and finance. His
achievements enhance our understanding of simulating constrained differential equations, Hamiltonian
systems, inverse problems, PDE-constrained optimization, and multiscale methods. Ascher's mark on the
practice of scientific computing is embodied in many highly cited publications, including three monographs and widely used software packages.
Prof. Andrea Damascelli
Affiliation: The University of British Columbia
Keywords: Condensed matter physics, quantum materials, electronic structure of solids, ARPES
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DAMASCELLI, Andrea - Department of Physics and Astronomy, The University of British Columbia
Damascelli’s research on the electronic structure of solids and the development of innovative spectroscopy techniques to study and manipulate quantum materials have led to pivotal contributions to the field of condensed matter physics. From uncovering the role of spin-orbit coupling in the superconductivity of Sr2RuO4 and Fe-based systems, to revealing charge order driven by Fermi-arc instabilities in cuprates, Damascelli’s pioneering work has bolstered and refocused the international community.
Prof. Lars Konermann
Affiliation: Western University
Keywords: protein structure and dynamics, mass spectrometry, biophysical chemistry
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KONERMANN, Lars - Department of Chemistry, Western University
Lars Konermann is an international leader in the area of mass spectrometry, with a research focus on the role of proteins in health and disease. His work has helped catalyze the transformation of mass spectrometry from a simple “mass” measurement tool to a comprehensive suite of techniques for interrogating protein structure, function, folding, dynamics, binding, and aggregation. Konermann’s advances have been recognized through a number of prestigious national research awards.
Prof. Richard Lockhart
Affiliation: Simon Fraser University
Keywords: statistical theory, asymptotics, model assessment, model selection, signal detection
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LOCKHART, Richard - Department of Statistics & Actuarial Science, Simon Fraser University
Richard Lockhart has made outstanding contributions to theoretical and applied statistics. His deep knowledge of analysis, probability, and statistical theory have enabled him to solve challenging problems in asymptotic distribution theory and the rigorous justification of statistical procedures. He is an international authority on goodness of fit, model assessment and model selection, and has provided clear statistical insights into signal and particle detection problems in the physical sciences.
LOCKHART, Richard - Département de statistique et d'actuariat, Université Simon Fraser
Richard Lockhart a contribué de manière remarquable aux statistiques théoriques et appliquées. Ses connaissances profondes de l’analyse, des probabilités et de la théorie statistique lui ont permis de résoudre des problèmes complexes de la théorie de distribution asymptotique et la justification rigoureuse des procédures statistiques. Il est une sommité internationale en ce qui concerne la qualité de l’ajustement, l’évaluation et la sélection de modèles et a fourni des solutions statistiques claires aux problèmes de détection des particules et des signaux dans le domaine des sciences physiques.
Prof. Ingrid Pickering
Affiliation: University of Saskatchewan
Keywords: X-ray absorption spectroscopy (XAS); heavy metals in the environment and human health
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PICKERING, Ingrid - Department of Geological Sciences, University of Saskatchewan
Ingrid Pickering is one of Canada’s most innovative environmental chemists. A Canada Research Chair in Molecular Environmental Science, her work has had an international impact on understanding the effects of heavy metals on the environment and human health. Her pioneering of synchrotron technologies has led to numerous highly cited studies on topics such as mercury in fish, the connection between selenium deficiency and arsenic poisoning, and plant uptake of metals.
Ingrid Pickering est une chercheuse mondialement reconnue dont les recherches fondées sur la technologie synchrotron qui ont grandement aidé à comprendre la toxicologie des métaux lourds sur la santé humaine. Chaire de Recherche du Canada en Science Environnementale Moléculaire, elle est l’auteur d’études pionnières très citées sur le mercure présent dans les poissons, le rapport entre la carence en sélénium et l’intoxication à l’arsenic, la spéciation du sélénium dans le sol et l’absorption du cadmium par les plantes.
Prof. Christopher Thompson
Affiliation: University of Toronto
Keywords: magnetars, neutron stars, gamma ray bursts, supernovae, magnetic fileds, plasma astrophysics, planet formation, planetesimals, formation of the Moon
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THOMPSON, Christopher - Canadian Institute for Theoretical Astrophysics, University of Toronto
Christopher Thompson is one of the world's top theorists in high energy astrophysics. His seminal papers
on plasma astrophysics, compact objects and planets are known for their great originality, deep physical
insight and technical virtuosity. Thompson is best known for his theory of the now ubiquitous magnetars,
neutron stars with very high magnetic fields, which have been spectacularly confirmed by observations
of soft gamma ray repeaters and anomalous X-ray pulsars.
Prof. Manuella Vincter
Affiliation: Carleton University
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VINCTER, Manuella - Department of Physics, Carleton University
Professor Manuella Vincter has made precision measurements of the electroweak force, the structure of the neutron and proton, and most recently the properties of the W and Z bosons, the carriers of the electroweak force. She played a leading role in the scientific development of the 3,000 member ATLAS collaboration, which in 2012 discovered the Higgs boson.
Prof. Luc Vinet
Affiliation: Université de Montréal
Keywords: Gauge theory, algebraic methods of mathematical physics, special functions,
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VINET, Luc - Département de physique, Université de Montréal
Luc Vinet’s work has a deep impact in our understanding of the role of symmetry in quantum mechanics, ranging from the role of supersymmetry in many basic quantum mechanical systems, to a much deeper comprehension of the structure of many important systems of special functions, simply by viewing them in terms of their algebra of symmetries. This latter work has had far ranging impact, notably in algebraic combinatorics
Prof. Yunjie Xu
Affiliation: University of Alberta
Keywords: Chirality Recognition/Transfer, Solvation, Non-covalent Interactions, Instrument Innovation
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XU, Yunjie - Department of Chemistry, University of Alberta
Yunjie Xu, Canada Research Chair in Chirality and Chirality Recognition, brings a rigorous physical sciences approach to decoding chiral phenomena. She advances the field by identifying important questions and finding answers by pushing methodical frontiers with the design and development of novel spectroscopic tools. Her profound contributions to uncovering stereospecific interactions underlying chirality recognition events, central to the biochemistry of life, have made her a world leader in chirality research.
Mme Valérie Amiraux
Affiliation: Université de Montréal
Keywords: Pluralisme religieux, minorités, musulmans, radicalisation
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AMIRAUX, Valérie - Département de sociologie, Université de Montréal
Valérie Amiraux est une spécialiste internationalement reconnue des minorités musulmanes dont la présence dans certaines sociétés (Allemagne, France, Grande-Bretagne, Italie, Québec) soulève des controverses. Ses recherches, s’appuyant sur des méthodologies qualitatives, ont contribué à introduire les critical race studies en sociologie des faits religieux et à proposer une théorisation du lien entre pluralisme et radicalisation