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Dr. Carol Cass
Affiliation: University of Alberta
Keywords: Nucleoside biology, nucleoside transporters, nucleoside therapeutics, cancer chemotherapy, membrane biochemistry
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Dr. Cass is internationally recognized for her research on membrane transport of nucleosides and nucleoside drugs. Her important early studies on nucleoside transport in human erythrocytes laid the foundation for the field and her subsequent studies of nucleoside transport deficiencies established that functional membrane transporters are essential for manifestation of cytotoxicity of many nucleoside drugs.
Dr. Mitchell Halperin
Affiliation: University of Toronto
Keywords: Acid-base, potassium, sodium, water, integrative physiology.
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Dr. Mitchell Halperin is internationally renowned for his expertise in and contributions to the clinical diagnosis and treatment of electrolyte and acid-base disorders. Through his creative endeavours he has changed our understanding of how the kidney regulates body metabolism. His contributions to education are widely acknowledged. Perhaps most striking is the fact that virtually every medical school in Canada, and many elsewhere in the world, are staffed by academic nephrologists whom he trained.
Dr. John Kelton
Affiliation: McMaster University
Keywords: Medicine, platelets, clotting
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John Kelton is a physician scientist whose investigation of platelet disorders and the management of these platelet disorders has led to international recognition. His research focussed on a study of platelets (tiny blood cells important for clotting) and diseases of these platelets. His basic studies have been complemented by clinical trials that have changed the management of many patients (for example, pregnant women with platelet disorders) around the world.
Dr. Edith McGeer
Affiliation: The University of British Columbia
Keywords: Alzheimer, parkinson, microglia, cytokines, complement
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Patrick and Edith McGeer's neurological research is recognized worldwide as responsible for many signal advances in the understanding of Alzheimer's disease and Parkinson's disease, and for the important kainic acid model of Huntington's disease. Their groundbreaking hypotheses on neuroinflammation in neurodegenerative diseases and anti-inflammatory therapy are now strongly supported and part of the main focus for research into Alzheimer's disease.
Dr. Patrick McGeer
Affiliation: The University of British Columbia
Keywords: Neuroscience, neuroinflammation, Alzheimer Disease, Parkinsonism
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Patrick and Edith McGeer's neurological research is recognized worldwide as responsible for many signal advances in the understanding of Alzheimer's disease and Parkinson's disease, and for the important kainic acid model of Huntington's disease. Their groundbreaking hypotheses on neuroinflammation in neurodegenerative diseases and anti-inflammatory therapy are now strongly supported and part of the main focus for research into Alzheimer's disease.
Dr. Richard Rachubinski
Affiliation: University of Alberta
Keywords: Peroxisome, organelle biogenesis, protein targeting, yeast genetics, peroxisome biogenesis disorders, trypanosomes, glycosomes, African sleeping sickness
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Richard Rachubinski is a leader in cell biology in the areas of protein targeting and organelle biogenesis. He has redefined our view of the formation of cell membranes and the movement of proteins across them. He has been the force behind a group of outstanding young biologists investigating the assembly of the varied membrane compartments making up the cell.
Dr. Peter St GEORGE-HYSLOP
Affiliation: University of Toronto
Keywords: Neurobiology, neurogenetics, neurological disease, neurochemistry, brain repair
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Peter St George-Hyslop is an international leader in research on neurodegenerative diseases. He pioneered the use of genetic approaches to elucidating the basis of these diseases. His research has provided insight into biological mechanisms regulating the disposition of membrane proteins associated with development and aging, and profoundly altered our understanding of neurodegeneration.
Dr. Michael Tyers
Affiliation: University of Toronto
Keywords: Biochemistry, genetics, genomics, cell division control, ubiquitin proteolytic systems
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Mike Tyers is distinguished for his work on regulation of the eukaryotic cell cycle by targeted protein degradation, for his analysis of MAP kinase signalling pathways, and for his application of proteomic techniques to the mapping of protein interactions. His research has fundamental implications for a broad range of biological processes.
Dr. Warwick Vincent
Affiliation: Université Laval
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Warwick Vincent is a world leader in polar microbial ecology. He has pioneered unique insights into microbial interactions that link the structure and functions of communities at the base of food chains in the Subarctic, Arctic and Antarctica. His research and ability to synthesize studies from different parts of the world are having a major influence in international polar science.
Dr. Cecil Yip
Affiliation: University of Toronto
Keywords: Peptide hormone receptors
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In a research career that spans three decades, Dr. Cecil Yip has published seminal papers that illuminate the structure and mechanism of the action of insulin and the insulin receptor. Among his contributions are the discovery of pre-proinsulin, proinsulin, and the insulin c-peptide. A three-dimensional reconstruction of the dimeric insulin receptor bound to insulin was his crowning achievement.
Dr. Robert Birgeneau
Affiliation: University of Toronto
Keywords: Phase transitions, neutron scattering, x-ray scattering, dimensionality effects, magnetism and superconductivity
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Robert J. Birgeneau is one of Canada's foremost experimental physicists and has made numerous original, and profound contributions to our understanding of condensed matter systems. He is widely known for his pioneering use of neutron and x-ray scattering in elucidating the nature of the phase transitions and excitations in many of the one-, two- or three-dimensional materials that have been and continue to be at the forefront of research in condensed matter and statistical physics.
Vidyadhar Godambe
Affiliation: University of Waterloo
Keywords: Inference, estimation, estimating functions, survey sampling, biostatistics
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Vidyadhar P. Godambe is internationally recognized as a major influence on the development of statistics over the past five decades. He has made outstanding and innovative contributions to the theory of estimation, formulating the methodology of estimating functions, leading and stimulating its further development, and promoting its application to diverse areas.
J. Peter Guthrie
Affiliation: Western University
Keywords: No barrier theory, prediction of rate constants, reaction mechanisms, thermodynamics, catalysis
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J. Peter Guthrie is a scientific leader in developing methods for the prediction of rate constants for chemical reactions in solution. He began with studies of the application of Marcus Theory to organic reactions, then developed Multidimensional Marcus Theory to treat concerted reactions in terms of the hypothetical stepwise reactions, and recently developed No Barrier Theory, which allows calculation of the rate constants for a great many reactions in solution with no adjustable parameters.
Dr. Sajeev John
Affiliation: University of Toronto
Keywords: Photonic crystals, optics, materials science
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Dr. Niky Kamran
Affiliation: McGill University
Keywords: Dirac operators, exterior differential systems, quasi-exactly solvable potentials, conservation laws, le pseudo-group.
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Niky Kamran, Department of Mathematics and Statistics, McGill University, is a leading researcher in the geometric study of differential equations. In a series of joint papers with Finster, Smoller and S. T. Yau, he has recently established sharp estimates for the long-time behaviour of Dirac fields in axisymmetric black hole geometries. His work on differential invariants and conservation laws for differential equations has led to an in-depth understanding of the property of geometric integrability for hyperbolic equations. He is also a founder of the rapidly expanding field of quasi-exactly solvable spectral problems in quantum mechanics. The growth of this field is due to a significant extent to his foundational papers. He is the recipient of the André Aisenstadt Prize in 1992, and is a Laureate of the Royal Academy of Sciences of Belgium. He won that academy's prize in mathematics in 1988 for his research monograph "Contributions to the study of the equivalence problem of Elie Cartan and its applications to partial and ordinary differential equations."
Dr. Neal Madras
Affiliation: York University
Keywords: Probability, self-avoiding walks, Monte Carlo methods, mathematical modelling, statistical mechanics
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Neal Madras is well known in the international mathematical and physics communities for his leading edge contributions to the rigorous theory of self-avoiding walks. He is also one of the leading contributors to the development and applications of more efficient Monte Carlo methods for the numerical simulation of self-avoiding walks, and has made significant contributions to the general mathematical theory of self-avoiding geometrical objects, which are important as lattice models of polymers.
Dr. George Sawatzky
Affiliation: The University of British Columbia
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George A. Sawatzky is recognized as one of the most respected researchers in the field of condensed matter. His pioneering work on the electronic structure of strongly correlated systems, and his contribution to the understanding of physical properties of transition metal oxides and the interplay between the spin, charge and orbital degrees of freedom have made him a much sought-after speaker at international conferences.
Dr. John Scheffer
Affiliation: The University of British Columbia
Keywords: Organic photochemistry, solid state chemistry, asymmetrick synthesis, structure-reactivity relationships, mechanism stuides
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John Scheffer has attained worldwide recognition for his pioneering research in the field of solid-state organic chemistry. Scheffer is the author of over 200 research publications and the recipient of a number of fellowships and awards, most recently the 2000 Alfred Bader Lecture Award of the Canadian Society for Chemistry.
Danial Wayner
Affiliation: National Research Council
Keywords: Surface chemistry, electrochemistry, physical organic chemistry, free radical chemistry, electron transfer, nanoscience, biofet
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Dan Wayner has made seminal contributions to the electrochemistry, kinetics and thermochemistry of organic free radicals and radical ions. His innovative studies provided the first comprehensive compilation of standard potentials of radicals, dramatically increased the store of reliable bond dissociation energies and generated many novel chemical probes of reaction mechanisms.
Dr. Stephen Withers
Affiliation: The University of British Columbia
Keywords: Enzymology, carbohydrates, mechanisms of reaction, glycosidases, proteins
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Professor Stephen Withers is one of the foremost authorities on the operation of glycosidases, enzymes that catalyze the decomposition of carbohydrate polymers like cellulose. His strategy for trapping glycosidase reaction intermediates is used in many laboratories worldwide. Withers recently showed that the textbook mechanism for the enzyme lysozyme, a mechanism taught to many hundreds of thousands of students each year, is incorrect.
Dr. Heather Munroe-Blum
Affiliation: McGill University
Keywords: Innovation, university research, science policy, psychiatric epidemiology, schizophrenia, personality disorder, children at risk
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Heather Munroe-Blum is a scholar and policy leader of international reputation. She is a leading figure in advancing the impact of university-based research in Canada, in championing effective science and innovation policy, as well as the positioning of Canadian higher education, research and researchers in the international context.
Thomas Pedersen
Affiliation: University of Victoria
Keywords: Climate history, isotopes, oceanography, marine chemistry
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Thomas Pedersen is a leading ocean scientist who has gained international recognition for his outstanding research into past changes in the state of Earth's oceans and climate, using chemical and isotopic tracers buried in the deposits on the sea floor, focussing especially on the global carbon cycle.
Dr. Hans Hofmann
Affiliation: McGill University
Keywords: Paleontology, stratigraphy, Precambrian, primitive fossils, biosedimentary strucutres
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Dr. Hans Hofmann is one of the world's leading experts on Precambrian life. He has developed techniques and criteria for distinguishing between biologically and physico-chemically produced structures in very ancient rocks, of potential value in future extra-terrestrial space exploration. His names for the subdivisions for the Precambrian time scale have been accepted by the International Union of Geological Sciences.
Dr. Michael Goodchild
Affiliation: University of California Santa Barbara
Keywords: Geography, geographic information systems, spatial analysis, digital libraries
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Michael Goodchild is the world academic leader in the formulation and development of Geographical Information Systems (GIS), computer-based data manipulations permitting rapid and accurate mapping of spatial attributes of phenomena. GIS is a global business that has grown explosively over the past two decades. Professor Goodchild's expertise is much sought after by national and international government agencies and private corporations concerned with a wide range of environmental, economic and social matters. He was educated at Cambridge and McMaster University and taught at the University of Western Ontario for twenty years before becoming Director of the National Centre for Geographic Information and Analysis, the US centre of excellence in this field.