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Profile

Prof. Jean Vance

Affiliation

University of Alberta

Academy or College

Academy of Science

Year Elected

2008

Areas of Interest

Cholesterol, Phospholipids, Lipoproteins, Neurons

Long Citation (for publication and press release)
Jean Vance's research on phospholipid and cholesterol metabolism is internationally recognized and is characterized by novelty and thoroughness. Her seminal work on specialized membranes associated with mitochondria changed the way biologists think about intracellular lipid transport. She developed and characterized three new strains of knock-out mice. Her research provides key insights into mechanisms of cholesterol and phospholipid transport in the brain. Jean has shown that lipid-containing particles in the brain dramatically protect neurons from death, suggesting potential clinical relevance for neurodegenerative disorders such as Alzheimer's disease. She explored mechanisms of lipid secretion into plasma with implications for cardiovascular disease.

Short Citation (to be read at the Induction Ceremony)
Jean Vance's research on phospholipid and cholesterol metabolism is internationally recognized and is characterized by novelty and thoroughness. Her seminal work on specialized membranes associated with mitochondria changed the way biologists think about intracellular lipid transport. She has developed and characterized three new strains of knock-out mice and her research provides key insights into mechanisms of cholesterol and phospholipid transport in the brain.