Profile
Prof. Jean Vance
Affiliation
University of AlbertaAcademy or College
Academy of ScienceYear Elected
2008Areas of Interest
Cholesterol, Phospholipids, Lipoproteins, Neurons
Long Citation (for publication and press release)
Jean Vance's research on phospholipid and cholesterol metabolism is internationally recognized and is characterized by novelty and thoroughness. Her seminal work on specialized membranes associated with mitochondria changed the way biologists think about intracellular lipid transport. She developed and characterized three new strains of knock-out mice. Her research provides key insights into mechanisms of cholesterol and phospholipid transport in the brain. Jean has shown that lipid-containing particles in the brain dramatically protect neurons from death, suggesting potential clinical relevance for neurodegenerative disorders such as Alzheimer's disease. She explored mechanisms of lipid secretion into plasma with implications for cardiovascular disease.
Short Citation (to be read at the Induction Ceremony)
Jean Vance's research on phospholipid and cholesterol metabolism is internationally recognized and is characterized by novelty and thoroughness. Her seminal work on specialized membranes associated with mitochondria changed the way biologists think about intracellular lipid transport. She has developed and characterized three new strains of knock-out mice and her research provides key insights into mechanisms of cholesterol and phospholipid transport in the brain.