Cancer, cell adhesion, translational research, biochemistry
DEDHAR, Shoukat, Department of Biochemistry and Molecular Biology, The University of British Columbia
Shoukat Dedhar’s pioneering work in the field of cell adhesion have uncovered the molecular basis of how cells in the body adhere to the surrounding matrix and how cell adhesion regulates fundamental aspects of cellular physiology. His discovery of Integrin-Linked Kinase has generated a large body of work which has demonstrated fundamental roles of this protein in normal tissue function and pathologies such as cardiovascular dysfunction, renal failure, and cancer.