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Benoît Roux
Affiliation
The University of ChicagoAcademy or College
Academy of ScienceYear Elected
2021Areas of Interest
Theoretical biophysics, molecular dynamics simulations, statistical mechanics, computational methods, membrane proteins, ion channels, tyrosine kinases, polarizable force fields.
Benoît Roux has performed ground-breaking computer simulations that have served to establish the physical principles governing the function of biological macromolecules. His innovative work has revealed the critical role that molecular flexibility and thermal fluctuations play in defining the function of ion channel and protein kinase. His contributions have fundamentally advanced our understanding of many problems, including cellular excitability and cancer biology.
Benoît Roux est un pionnier des simulations informatiques établissant les principes physiques qui régissant le fonctionnement des macromolécules biologiques. En particulier, ses travaux ont révélé le rôle essentiel de la flexibilité moléculaire et des fluctuations thermiques dans la fonction des canaux ioniques et des protéines kinases. Ses contributions ont fondamentalement fait progresser notre compréhension de nombreux problèmes biologiques, notamment l’excitabilité cellulaire et la biologie du cancer.