Profile
Dr. Brenda Andrews
Affiliation
University of TorontoAcademy or College
Academy of ScienceYear Elected
2005Areas of Interest
Genetics, cell cycle, cell biology, gene expression, functional genomics
LONG CITATION
Professor Brenda Andrews research deals with the cell cycle, a central function in all living organisms. Using yeast as a model system, she identified crucial transcription factors that govern a key step in the cell cycle; these studies have led to an appreciation of the molecular mechanisms governing expression of hundreds of cell cycle genes. Dr Andrews has elucidated the action of an important cell-cycle kinase, Pho85, which governs many cellular processes including metabolism, division and polarized growth, and whose mammalian counterpart plays key roles in neurogenesis. Her work has yielded extraordinary insight into the workings of the cell-division machinery in all organisms and is a prototype for cell-cycle studies.
SHORT CITATION
Professor Brenda Andrews has made important contributions to our understanding of how all cells control their division. Her internationally-recognized work has become the model for cell-division research and has yielded extraordinary insight into how the cell-division machinery functions and its malfunctioning in disease.