Paul Jolicoeur
Fellow
Current Employer
Université de Montréal
Election Year
1989
Academy
Academy of Science
Discipline
Medical Sciences
Department
Laboratoire de biologie moléculaire
Paul Jolicoeur (M.D., Ph.D.) is Director of the Molecular Biology Laboratory of CRIM and an eminent biomedical researcher in the field of retroviruses and cancer. Major contributions have been on the molecular control of the Fv-1 gene, on the identification of several determinants of pathogenecity of murine leukemia retroviruses and on the isolation of revertant cells which are an extraordinary tool to study the interaction of cellular genes with the oncoprotein V-Fos. One of these retroviruses produces paralysis and neurological lesions similar to those produced by the AIDS virus. Jolicoeur has identified and cloned a defective retrovirus responsible for MAIDS (murine acquired immunodeficiency syndrome).
Recently his laboratory has developed a novel model of Aids in mice expressing HIV-1.
Recently his laboratory has developed a novel model of Aids in mice expressing HIV-1.