Dr. Charles Boone
Fellow
Current Employer
University of Toronto
Election Year
2005
Academy
Academy of Science
Discipline
Molecular Biology and Genetics
Department
Banting & Best Department of Medical Research, CCBR
Keywords
Yeast molecular genetics, functional genomics, signal transduction, fungal pathogenesis
LONG CITATION
Professor Charles Boone is a yeast molecular geneticist of international stature and a leader among the current generation of rising biomedical researchers in Canada. While his research centres on components of signal-transduction pathways in yeast that affect developmental functions, perhaps his most important contribution has been his most recent. He has developed an automated method of carrying out genome-wide synthetic-lethal tests involving millions of yeast genetic crosses. This method enables a simple determination of genetic, and by inference gene-product, interactions in yeast and is, in principle, applicable to other organisms. It has gained Dr Boone great international recognition, and places him among the most visible genome researchers in the world.
SHORT CITATION
Professor Charles Boone is a leading yeast molecular geneticist renowned for his pioneering research. Still early in his career, he has made enormous contributions to our understanding of signal transduction and how cells change their shape. He is leading a collaborative network of researchers who are using genomics to determine how genes interact.
Professor Charles Boone is a yeast molecular geneticist of international stature and a leader among the current generation of rising biomedical researchers in Canada. While his research centres on components of signal-transduction pathways in yeast that affect developmental functions, perhaps his most important contribution has been his most recent. He has developed an automated method of carrying out genome-wide synthetic-lethal tests involving millions of yeast genetic crosses. This method enables a simple determination of genetic, and by inference gene-product, interactions in yeast and is, in principle, applicable to other organisms. It has gained Dr Boone great international recognition, and places him among the most visible genome researchers in the world.
SHORT CITATION
Professor Charles Boone is a leading yeast molecular geneticist renowned for his pioneering research. Still early in his career, he has made enormous contributions to our understanding of signal transduction and how cells change their shape. He is leading a collaborative network of researchers who are using genomics to determine how genes interact.