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Morley Hollenberg

Fellow
Current Employer
University of Calgary
Election Year
2003
Academy
Académie des sciences
Discipline
Medical Sciences
Department
Faculty of Medicine
Keywords
Pharmacology, signal transduction, drug action, endocrinology, medicine
LONG
Dr. Morley Hollenberg's training in chemistry (M.Sc. 1964), pharmacology (D.Phil., 1967) and medicine (M.D./Internship, 1972) has provided the essential background for his research. He is internationally recognized for his work on the biosynthesis, receptor pharmacology and signaling mechanisms of hormones and growth factors as well as the novel signaling by and physiology of proteinase-activated receptors (PARs). His work has been key to documenting the role of PARs as unique receptors involved in inflammation, vasoregulation and nociception, thereby identifying novel therapeutic targets for diseases ranging from cancer to inflammatory bowel disease and chronic pain.

SHORT
Dr. Morley Hollenberg's research is on the biosynthesis, receptor pharmacology and signaling mechanisms of hormones and growth factors as well as the novel signaling by and physiology of proteinase-activated receptors (PARs). In documenting the role of PARs as unique receptors involved in inflammation, vasoregulation and nociception, he has been key in identifying novel therapeutic targets for diseases.
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