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Dr. Dennis Vance

Fellow
Current Employer
University of Alberta
Election Year
1996
Academy
Académie des sciences
Discipline
Microbiology and Biochemistry
Department
Department of Biochemistry
Keywords
Phosphatidylcholine, lipoproteins, atherosclerosis
Dennis E. Vance, Director of the Lipid and Lipoprotein Research Group at the University of Alberta and Heritage Medical Scientist, is an international leader in lipid biochemistry and the foremost author of advanced and undergraduate texts on lipids. He has made substantial contributions to an understanding of glycerophospholipid metabolism by identifying the regulatory and rate limiting enzymes in phosphatidylcholine biosynthesis and by isolating and cloning the enzymes involved in the methylation of phosphatidylethanolamine. He has effectively utilized the readily induced choline deficiency of rat liver to demonstrate an important role for phosphatidylcholine biosynthesis in lipoprotein secretion.
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